Sangre de Grado is a tree that grows in the Amazon region of South America. The tree bark and sap are used to make medicine. Sangre de Grado, one of the chemicals it contains, is used for diarrhea associated with cholera, AIDS, traveling, or treatment with antibiotics. Sangre de Grado is also used for treating cancer, irritable bowel syndrome (IBS), viral respiratory infections, fever, hemorrhage, bleeding gums, wounds, broken bones, vaginal infections, hemorrhoids, a skin condition called eczema, and insect bites and stings. Other uses include treating ulcers of the mouth, throat, stomach, or intestine; supporting the body’s tissue repair mechanisms; and as a general tonic.